Intraductal Papilloma
An intraductal papilloma is a small benign tumor that forms within the milk duct in the breast. Intraductal papilloma can be solitary (single) or multiple (papillomatosis).
Difference |
Solitary / Single Papilloma |
Multiple Papillomatosis |
Location |
Formed in large duct nearer the nipple |
Formed in smaller ducts further away from nipple |
Risk of developing breast cancer |
Not associated with risk of breast cancer |
Are associated with slightly higher risk of breast cancer and also linked to precancerous breast condition known as atypical hyperplasia |
Symptoms and Signs
- Breast lumps near the nipple or retroareolar area
- Unusual nipple discharge which is persistent and spontaneous
- Discharge can be clear or bloody
- Discharge are usually from a single duct
Diagnosis and Investigation
- Breast imaging with mammogram / ultrasound
- Breast biopsy for palpable lump
- Ductogram for nipple discharge (not commonly performed in most centres due to low sensitivity and specificity)
Treatment
- Surgical excision of the affected duct with the intraductal lesion known as Microdochectomy
A lacrimal probe is used to locate the duct with discharge and the entire duct will be removed surgically for histopathological examination (HPE)
The entire breast duct removed showing the intraductal mass within
Follow Up
- Regular screening and regular follow up for those diagnosed with multiple papillomatosis and atypical hyperplasia